Hi, I am Xu Chang. In 2023, I received a Ph.D. in Biomedical Engineering from Harbin Institute of Technology. Before joining Liu's lab, I was mainly engaged in protein interaction research, spatial omics algorithm development, and spatial data analysis of the human brain. I am currently developing spatial and single-cell multi-omics integration algorithms, and am also interested in cancer genomics and developmental biology. During my spare time, I would like to play badminton, swim and do fitness.
Publications:
Chang Xu#, Xiyun Jin#, Songren Wei#, Pingping Wang, Ying Hu, Guohua Wang, Qinghua Jiang*. DeepST: identifying spatial domains in spatial transcriptomics by deep learning. Nucleic Acids Research, 2022,50(22):gkac901.
Wenyang Zhou#, Chang Xu#, Pingping Wang, Anastasia A Anashkina, Qinghua Jiang*. Impact of mutations in SARS-COV-2 Spike on viral infectivity andantigenicity. Briefings in Bioinformatics, 2021 Sep;13:bbab375.
Wenyang Zhou#, Chang Xu#, Meng Luo, Pingping Wang, Yiqun Li, Huan Nie, Qinghua Jiang*, Anastasia A Anashkina*. MutCov: a pipeline for evaluating the effect of mutation in spike protein on infectivity and antigenicity of SARS-CoV-2. Computers in Biology and Medicine, 2021 Jun; 145:105509.
Wenyang Zhou#, Chang Xu#, Liran Juan, Anastasia A Anashkina, Huan Nie, Qinghua Jiang*. N439K Variant in Spike Protein Alter the Infection Efficiency and Antigenicity of SARS-CoV-2 Based on Molecular Dynamics Simulation. Frontiers in Cell and Developmental Biology, 2021 Aug;9:697035.